drug delivery study of tamoxifea with single walled carbon nanotobes

نویسندگان

k. shahanipour

a.h. esmailian

f. mollaamin

b. khalili hadad

چکیده

as drug delivery systems nanoparticulan widely investigated because of many advantages such as smaller size,controlled drug release potential targeting ability, enhancement of therapeutic efficacy and reduction oftoxicity. so, carbon nanotubes have recently received considerable attention as alternative drug delivery carrierin this study we investigate interaction of tamoxifen with open-end of shgle-walled carbon nanotubes (swnts)using the gaussian 98 program. we have computed nmr shielding tensors at biltp and hf levels by using 3-21g and 570-36 basis sets in the water. our results reveal that nmr chemical shielding parameters arestrongly affected by inducing solvent media. regarding to our plotted graph f pp, do, , 8 in differentmethods and basis sets, the largest crw values obtained for op atom at the 11f in sto-30 whereas the smallestone belonged to cp. it is interestusg to note that the opposite trend have been observed for asymmetryparameterseal

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Drug Delivery study of Tamoxifea with Single Walled Carbon Nanotobes

As drug delivery systems Nanoparticulan widely investigated because of many advantages such as smaller size,controlled drug release potentiaL targeting ability, enhancement of therapeutic efficacy and reduction oftoxicity. So, carbon nanotubes have recently received considerable attention as alternative drug delivery carrierIn this study we investigate interaction of tamoxifen with open-end of ...

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عنوان ژورنال:
journal of physical & theoretical chemistry

ISSN

دوره 7

شماره 1 2010

کلمات کلیدی

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